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Stephen Sonis Selected Research

Stomatitis

10/2021Concordance of the WHO, RTOG, and CTCAE v4.0 grading scales for the evaluation of oral mucositis associated with chemoradiation therapy for the treatment of oral and oropharyngeal cancers.
1/2020Randomized Phase 2 Trial of a Novel Clonidine Mucoadhesive Buccal Tablet for the Amelioration of Oral Mucositis in Patients Treated With Concomitant Chemoradiation Therapy for Head and Neck Cancer.
1/2017Impact of a planned dose interruption of dacomitinib in the treatment of advanced non-small-cell lung cancer (ARCHER 1042).
9/2014Emerging therapies for the prevention and treatment of oral mucositis.
8/2013Oral ulcers in patients with advanced breast cancer receiving everolimus: a case series report on clinical presentation and management.
4/2013A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients.
10/2011Clinical presentation and management of mTOR inhibitor-associated stomatitis.
10/2011Personalized medicine for mucositis: Bayesian networks identify unique gene clusters which predict the response to gamma-D-glutamyl-L-tryptophan (SCV-07) for the attenuation of chemoradiation-induced oral mucositis.
7/2010AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis.
10/2009Randomized phase 2 study of concomitant chemoradiotherapy using weekly carboplatin/paclitaxel with or without daily subcutaneous amifostine in patients with locally advanced head and neck cancer.
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Stephen Sonis Research Topics

Disease

17Neoplasms (Cancer)
01/2022 - 07/2003
17Stomatitis
10/2021 - 12/2003
10Mucositis
09/2014 - 12/2003
4Head and Neck Neoplasms (Head and Neck Cancer)
01/2020 - 04/2007
3Xerostomia
10/2009 - 07/2003
3Graft vs Host Disease (Graft-Versus-Host Disease)
05/2005 - 11/2002
2Pneumonia (Pneumonitis)
01/2020 - 05/2004
2Breast Neoplasms (Breast Cancer)
01/2018 - 08/2013
2Prostatic Neoplasms (Prostate Cancer)
01/2017 - 01/2014
2Diarrhea
01/2017 - 02/2015
2Fatigue
01/2017 - 01/2014
2Oral Ulcer (Mouth Ulcer)
08/2013 - 10/2011
2Infections
05/2007 - 05/2007
2Fever (Fevers)
05/2007 - 05/2007
1Oral Manifestations
01/2022
1Dental Caries (Decay, Dental)
11/2021
1Oropharyngeal Neoplasms
10/2021
1Ventilator-Associated Pneumonia
01/2020
1Deglutition Disorders (Dysphagia)
01/2020
1Hypotension (Low Blood Pressure)
01/2020
1Nausea
01/2020
1Arthralgia (Joint Pain)
01/2018
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017
1Pain (Aches)
10/2011
1Candidiasis (Moniliasis)
10/2011
1Periodontitis
04/2011
1Periodontal Diseases (Periodontal Disease)
04/2011
1Inflammation (Inflammations)
04/2011
1Aphthous Stomatitis (Aphthous Ulcer)
01/2010
1Squamous Cell Carcinoma of Head and Neck
10/2009
1Colorectal Neoplasms (Colorectal Cancer)
01/2008
1Multiple Myeloma
05/2007
1Hematologic Neoplasms (Hematological Malignancy)
05/2007
1Carcinoma (Carcinomatosis)
01/2006

Drug/Important Bio-Agent (IBA)

4Narcotics (Narcotic Analgesics)IBA
05/2007 - 01/2004
3EverolimusFDA Link
08/2013 - 10/2011
3ridaforolimusIBA
04/2013 - 01/2010
2Pharmaceutical PreparationsIBA
09/2014 - 08/2013
2MTOR InhibitorsIBA
10/2011 - 01/2010
2Interleukin-1 (Interleukin 1)IBA
04/2011 - 11/2002
2MouthwashesIBA
07/2010 - 01/2004
2CytokinesIBA
10/2009 - 11/2002
2Sirolimus (Rapamycin)FDA Link
05/2005 - 05/2004
2Methotrexate (Mexate)FDA LinkGeneric
05/2005 - 05/2004
1Immune Checkpoint InhibitorsIBA
01/2022
1TabletsIBA
01/2020
1Clonidine (ST 155)FDA LinkGeneric
01/2020
1Aromatase InhibitorsIBA
01/2018
1Estrogens (Estrogen)FDA Link
01/2018
1dacomitinibIBA
01/2017
1Fibroblast Growth Factor 7FDA Link
09/2014
1exemestane (Aromasin)FDA Link
08/2013
1Hormones (Hormone)IBA
08/2013
1temsirolimusFDA Link
04/2013
1golotimodIBA
10/2011
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2011
1Trefoil Factor-1IBA
07/2010
1TOR Serine-Threonine KinasesIBA
01/2010
1InterleukinsIBA
10/2009
1Carboplatin (JM8)FDA LinkGeneric
10/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2009
1Amifostine (Ethyol)FDA LinkGeneric
10/2009
1Paclitaxel (Taxol)FDA LinkGeneric
10/2009
1Melphalan (Alkeran)FDA LinkGeneric
05/2007
1Opioid Analgesics (Opioids)IBA
04/2007
1Biological ProductsIBA
06/2006
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2005
1Tacrolimus (Prograf)FDA LinkGeneric
05/2004
1Calcineurin InhibitorsIBA
05/2004
1IceIBA
12/2003
1Benzydamine (Tantum)IBA
12/2003
1Granzymes (Granzyme)IBA
11/2002
1PerforinIBA
11/2002
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
11/2002

Therapy/Procedure

10Therapeutics
11/2021 - 06/2006
10Radiotherapy
01/2017 - 07/2003
8Drug Therapy (Chemotherapy)
02/2015 - 12/2003
5Chemoradiotherapy
10/2009 - 12/2003
4Total Parenteral Nutrition
05/2007 - 05/2005
3Hematopoietic Stem Cell Transplantation
05/2007 - 05/2005
2Precision Medicine
12/2021 - 10/2011
2Low-Level Light Therapy (LLLT)
04/2020 - 01/2020
2Oral Hygiene (Dental Hygiene)
01/2020 - 01/2004
2Drug Tapering
04/2013 - 10/2011
2Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
05/2005 - 05/2004
1Immunotherapy
01/2022
1Duration of Therapy
11/2021
1Home Nursing (Nursing, Home)
01/2020
1Mechanical Ventilators (Ventilator)
01/2020
1Palliative Care (Palliative Therapy)
01/2017
1Oral Medicine
10/2011
1Transplantation
05/2007
1Enteral Nutrition (Feeding, Tube)
04/2007
1Analgesia
05/2005
1Stem Cell Transplantation
05/2004
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
11/2002